Renieramycin M (RM) is a Food Storage Containers KCN-stabilized tetrahydroisoquinoline purified from the blue sponge Xestospongia sp., with nanomolar IC50s against several cancer cell lines.Our goal is to evaluate its combination effects with doxorubicin (DOX) in estrogen receptor positive MCF-7 breast cancer cells.MCF-7 cells were treated simultan
Automobile manufacturers have been contributing a large quantity of carbon emission on the earth for decades.This study examined an environmental impact problem of an automobile ignition coil within a supply chain.An assessment based on the methodology of Life Cycle Assessment to certify total carbon emission that a product contributes to the envir
Genome-wide association studies (GWAS) have identified THADA as one of the susceptibility genes for polycystic ovary syndrome (PCOS).Single nucleotide polymorphisms (SNPs) in the THADA gene showed significant over-transmission in PCOS and strong correlations with testosterone level.However, there was insufficient evidence to verify the effect of TH
Helicobacter pylori (H.pylori) is found everywhere (approximately 50%) in people in the world, causing various types of gastrointestinal diseases ranging from mild inflammation, ulcers, and sometimes, stomach cancer.This pathogen carries a diverse set of genes encoding several virulence factors.In this research, we look forward to isolating bacteri
Traditional ecological knowledge (TEK) shapes human-environment interactions across much of the globe.Numerous case studies have provided evidence of TEK degradation, with substantial implications for the status of biodiversity.Previous studies draw on diverse academic disciplines, each with a unique set of theoretical constructs and discipline-spe